Health in the News
Smoking a bad habit or profitable disease?
June 2008
A recent article in the Annals of Medicine suggests that the smoking habit should be reclassified as a disease.
The authors say, "For smokers using long-term cessation medications, health care providers should encourage treatment and insurance carriers should cover it
Tobacco dependence treatments are often limited. Tobacco dependence should share the status of other chronic illnesses, with effective treatments given as long as is necessary to achieve successful clinical outcomes."
Dr. Grout's Comment:
This is a fascinating, behind-the-scenes look at the maneuverings of the pharmaceutical industry to create an ever widening market for drugs in the United States. They are planting the idea that to quit smoking, you need prescription drugs and those should be paid for by health insurance because smoking is a chronic illness like diabetes.
The authors of this article declared conflicts of interest with the drug companies Pfizer, Novartis, GlaxoSmithKline, and Celtic Pharma.
Does "long-term cessation medications" mean that people will essentially transfer their addiction from the tobacco companies to the pharmaceutical industry? Studies have shown that existing medicinal nicotine substitutes are far from harmless. Buproprion, a common nicotine substitute, has been known to cause seizures. And the substitute varenceline has been linked to psychiatric disturbances including suicides.
CNN's Lou Dobbs blasts FDA's incompetence
June 2008
CNN reports the FDA office in charge of food safety has seen its workload increase more than 20 percent in recent years. But the FDA's Center for Food Safety and Applied Nutrition has had its staffing and budget cut 14 percent from 2003 to 2006.
Most of the cuts came in the field, those in charge of inspecting the food consumers eat. The GAO says in 2001 there were 211 inspections of foreign food companies; last year only 96. But the problems for the agency date back even further.
The Department of Health and Human Services estimates that the current tomato outbreak will cost the national tomato industry more than 100 million. "Why did hundreds of people have to be sickened before the FDA acted?" asked CNN anchor Lou Dobbs. "The FDA doesn't know where the salmonella came from. The FDA doesn't have any positive evidence in a tomato of salmonella. They don't know anything about the distribution system; they don't know anything about the packing operations, the farms themselves, are only this weekend sending inspectors into the field. Now they're saying that this outbreak has its origins are in both Florida and Mexico? That defies credulity. I mean this is just unbelievable. Sheer brazen incompetence. And there still isn't any hard evidence that the salmonella is in the tomatoes. This salmonella outbreak underscores the FDA's utter inability to protect the American consuming public."
Dr. Grout's Comment:
When the FDA's advisory panels are filled with conflicts of interest, filled with people who have various ties with the industry, the agency cannot expect to operate in the public interest.
We've seen prior problems with tomatoes, we've had the e. coli scare in the spinach field, we've had to recall tons of beef
. The food is recalled, or we are told to cook it longer. But no where is there a call to change industry farming methods which encourage the growth of e. coli and salmonella.
This voices of dissatisfaction with the FDA's mission to protect the public has moved beyond advocacy groups now to the mainstream media. It will be interesting to see how the next presidential administration handles this hot potato.
MSG to be reviewed by FDA
June 2008
After decades of concern about the safety of the food additive MSG in food, and mounting evidence about the adverse reactions many people have to it, the FDA is considering a petition to remove monosodium glutamate from the GRAS (generally regarded as safe) list of ingredients.
This action would stop hundreds of food manufacturers, from Campbell's to Heinz, and thousands of restaurants, from Kentucky Fired Chicken to Applebees, from using this additive.
Since 1950, food manufacturers and restaurants have discovered that adding MSG to food makes people eat more of it, and eat more quickly. MSG is addictive, like nicotine for food.
The petition says: "There are few chemicals that we are exposed to that have as many far reaching physiological affects on living beings as Monosodium Glutamate does. MSG directly causes obesity, diabetes, triggers epilepsy, destroys eye tissues, is genotoxic in many organs and is the probable cause of ADHD and Autism. Considering that MSG's only reported role in food is that of `flavor enhancer' is that use worth the risk of the myriad of physical ailments associated with it? Does the public really want to be tricked into eating more food and faster by a food additive? MSG is entering our bodies in record amounts with absolutely no limits."
The use of MSG has become controversial in the past 30 years because of adverse reactions in people who've eaten foods that contain MSG. Research on the role of glutamate--a group of chemicals that includes MSG--in the nervous system also has raised questions about the chemical's safety.
Dr. Grout's Comment:
After WWII ended, the American military was curious to find out why the Japanese field rations tasted so much better. Turned out the secret ingredient was MSG, and that began the large-scale use of it in the United States. MSG makes our brain declare that food tastes really, really good and that we want more of it, regardless of nutritive value.
MSG simulates umami, one of the five basic tastes which the human tongue can recognize and appreciate. Specifically, umami is the taste associated with savoriness, as found in foods such as meat, cheese, tomatoes, and mushrooms. These foods contain naturally formed glutamates, which is what gives them that savory taste. Unfortunately, MSG, like aspartame, is also toxic to the brain.
MSG can be used without disclosure - you won't find it find it listed on the label. Instead, it might be called one of perhaps 50 names including hydrolyzed protein, soy protein, maltodextrin, or natural flavor. It might be in the milk solids in low fat milk. MSG is found in most soups, salad dressings, processed meats, frozen entrees, ice cream, and frozen yogurt, in some crackers, bread, canned tuna, and very often in "low fat" and "no fat" foods to make up for flavor lost when fat is reduced or eliminated. It can be found in cosmetics, pharmaceuticals, dietary supplements and infant formula. It is found in vaccines -- including vaccines used on children. It can be used in waxes applied to fresh fruits and vegetables and it sprayed on vegetable crops and nuts in the fields. California wine grapes are sprayed with MSG.
You can read the petition at http://www.regulations.gov/fdmspublic/component/main?main=DocketDetail&d=FDA-2007-P-0178. You can also read Neurosurgeon Dr. Russell Blaylock's book entitled, "Excitotoxins, The Taste That Kills."
Baby Boomers fuel "brain fitness" market
June 2008
Teenagers cramming for tests and people worried about "senior moments" can now turn to an explosion of brain-assisting video games, such as Nintendo's Brain Age; puzzles that are said to ward off dementia, such as Sudoku and crosswords; and online tips that claim to train the brain.
"This is not just a Nintendo-fueled fad," says Alvaro Fernandez, CEO & Co-Founder of SharpBrains, a market-research firm. "The brain fitness market passed a tipping point in 2007 thanks to the convergence of a very proactive boomer generation hitting their 60s."
Many boomers have watched their parents struggle with Alzheimers, and an estimated 10 million of them are now expected to develop the disease, according to a recent report from the Alzheimer's Association.
"People are worried," says Dr. John Hart Jr., medical science director of the Center for BrainHealth at the University of Texas at Dallas. "You have a large group of the population getting to the age where they are sort of vulnerable to degenerative neurological diseases that seem to be prevalent."
Hart says there is "reasonable evidence" that challenging your brain by learning new things can stave off the cognitive decline that comes with aging. But brain fitness programs differ from traditional learning by focusing on drills for specific cognitive abilities, such as concentration and retaining information.
"I am hoping that in the future, you will be able to go a health care provider or other expert who will be able to give folks a brain physical" and prescribe the proper exercises, he says.
Dr. Grout's comment:
The future has arrived. At the Arizona Center for Advanced Medicine we evaluate brain function as well as body function, through our BrainAdvantage program, and prescribe a program which will help improve memory, judgment and metabolism all in one location. You no longer have to go to a traditional doctor for blood work, a holistic doctor or naturopath to look at functional tests, and a neuropsychologist to work with your brain. Now you can do it all at the same time, in the same place. Please call us for more information.
Heart surgery not linked to cognitive decline
June 2008
Heart patients often experience lasting problems with memory, language, and other cognitive skills after bypass surgery. However, these problems aren't caused by the surgery itself or the pump used to replace heart function during surgery, a new study by Johns Hopkins researchers suggests.
The study compared cognitive function of patients who received cardiac bypass surgery with that of patients who received other treatments for coronary artery disease, including pharmaceuticals and stents. After testing all the study subjects periodically in a variety of cognitive areas for six years after their treatments, the researchers found that both groups experienced an almost identical decline in cognitive function.
The results suggest that the disease itself, and not any particular treatment, is the cause for cognitive decline.
Previous studies linked bypass surgery to patients' mental decline. Many doctors blamed the bypass pump that keeps blood flowing through the body during surgery and therefore did not recommend surgery to their patients.
Hopkins researcher Guy McKhann says he and other researchers believe coronary artery disease is the culprit. However, he says, they don't believe cognitive decline is an inevitable consequence of heart disease.
"If we take a very aggressive approach to treating risk factors for heart disease, including keeping a handle on diabetes, blood pressure, and weight, patients may be able to avoid these cognitive problems," McKhann says.
Dr. Grout's Comment:
It is always a good thing to test myths. So now we know, at least from this one study, that we see similar cognitive decline in people with coronary artery disease, both in those who had surgery (bypass grafts) and in those who did not. So, the questions then become: If "the disease itself is the basis for cognitive decline," are the medications at fault? There is much antidotal evidence that statin drugs for example cause cognitive problems and they are often prescribed to those with "high cholesterol" who are said to be at risk for heart disease. What are the side effects of the drugs given for diabetes and high blood pressure? Is memory loss just a normal part of aging? The study does not appear to address any sort of nutritional or lifestyle alternation, which could have a significant effect on the outcome, even after heart disease has become manifest. The most effective treatment of any chronic illness is modification of nutrition and lifestyle. The Arizona Center for Advanced Medicine offers FirstLine Therapy to help you make the nutritional and lifestyle changes, and we can treat the brain function itself with our BrainAdvantage program.
Sunshine–vitamin D–is the new wonder drug
June 2008
According to a study published in the June 9 issue of the Archives of Internal Medicine, men with low levels of vitamin D have more than twice the risk of heart attack. In this study, 18,000 men were studied for 10 years. Those classified as deficient in vitamin D were about 2.5 times more likely to have a heart attack than those with higher levels of the vitamin.
Just last week, another study found that low levels of vitamin D increased the risk of diabetes. And a study released last month linked deficiencies to an increased risk of dying from breast cancer.
Until recently, vitamin D was viewed primarily as a protective agent against bone disease. Researchers are suggesting that the new studies should prompt the government to reconsider the RDA levels for vitamin D.
Dr. Grout's Comment:
Despite the amount of sun that we see in Arizona, about 98% of my patients have vitamin D levels which are far below the levels recommended by the Vitamin D council. About 5% have levels below the reference range in lab tests which are the levels required to prevent rickets. About 20 minutes of exposure to the sun each day, in a skimpy bathing suit, without sunscreen, will help the body manufacture close to 20,000 IU of Vitamin D. Or you can take a pill
or a drop. Does too much sunshine cause skin cancer? Read up on it in our library article, "Skin Cancer, Sunshine, and Vitamin D." As more information like this breaks into the mainstream media, the day will come when we retire the mantra "stay out of the sun it will give you cancer" just as we tossed out the advice from "experts" a decade ago that a high carbohydrate diet was the way to go. Vitamin D is good for us; we need more of it.
Prescribing antidepressants for stroke
May 2008
Doctors may want to give stroke victims antidepressants right away instead of waiting until they develop depression, a common complication, new research suggests.
The researchers gave low doses of the antidepressant Lexapro to stroke patients. The patients on the drug were 4.5 times less likely to develop depression than patients taking a dummy pill.
The study, appearing in Wednesday's Journal of the American Medical Association, was based on an analysis of 176 stroke patients, ranging in age from 50 to 90.
Someday high-risk people like stroke patients might take the drugs before suffering depression just as people now take cholesterol drugs to prevent heart attacks, the lead author said.
More than 700,000 Americans suffer strokes each year and more than one-third will develop depression in the next two years. Stroke patients with depression recover more slowly and are more likely to die, according to previous research.
"We showed you could in fact prevent the development of depression after stroke,'' said Dr. Robert Robinson of the University of Iowa who led the study." I hope I don't have a stroke, but if I do, I would certainly want to be placed on an antidepressant.''
But with prevention, some patients take pills who never would have needed them, putting them at risk for unnecessary side effects. Seven stroke patients would have to be treated with antidepressants to prevent one depression, the researchers found.
Dr. Grout's Comment:
Even if Lexapro is given to make what serotonin the brain can still produce hang around longer, this does nothing to help the brain recover from its stroke. Whenever there is a stroke, there are always brain cells in the surrounding area which are partially damaged but not yet dead the area is called the "penumbra" or "shadow zone". These cells still have a chance to recover, if they can be given sufficient energy. However, because of the stroke, their blood supply has been cut off or diminished to the point where they have used up all their stores of readily available energy (ATP) and have used up all the precursors. So they are left with no gas in the tank. Giving ribose helps to put at least a precursor of gas in the tank, so that the cells have a better chance at surviving.
GMO sugar is here and everywhere
May 2008
American Crystal, a large Wyoming-based sugar company, and several other leading U.S. sugar providers have begun sourcing their sugar from genetically engineered (GE) sugar beets.
Like GE corn and GE soy, products containing GE sugar will not be labeled as such. These sugars, like GE corn and soy, are found in many conventional food products, so consumers will be exposed to genetically engineered ingredients in just about every non-organic multiple-ingredient product they purchase.
The GE sugar beet is designed to withstand strong doses of Monsanto's controversial broad spectrum Roundup herbicide. Farmers planting GE sugar beets are told they may be able to apply the herbicide up to five times per year. Weed control is the number one production problem facing sugarbeet growers in the USA; some industry experts say weeds can sap as much as 30 percent of a crop's yield.
"It's a pretty major step," Crystal President David Berg said. "Here at American Crystal, we believe biotechnology is the current wave that will help feed the world."
Dr. Grout's Comment:
Since half of the granulated sugar in the U.S. comes from sugar beets, a move towards biotech beets marks a dramatic alteration of the U.S. food supply. Sugar beets have been modified to insert a gene that makes the plant resistant to glyphosate, a toxic herbicide, sold under the trade name Roundup. At the request of Roundup's manufacturer, Monsanto, the EPA increased the allowable amount of glyphosate residues on sugar beet roots by 5,000 percent. The inevitable result is more pesticide in our sugar, and a GM element "hiding" in many items we might by at the grocery store.
According to a recent CBS News/New York Times poll, 53 percent of Americans say they won't buy food that has been genetically modified. But much of it is not labeled. One way to avoid GM is to buy organic.
Check out www.DontPlantGMOBeets.org. The Interfaith Center on Corporate Responsibility, a coalition of nearly 300 faith-based institutional investors, launched this Web-based campaign in March, 2008, "because of weak governmental review and oversight, and the lack of long-term, independent and peer-reviewed safety studies."
Jeffrey Smith, author of Seeds of Deception, and Bob Gregory launched the "GM Free Churches" campaign in Virginia to educate churches about the health and spiritual dangers of GMO-ed foods.
More than half of us are on drugs
May 2008
For the first time, it appears that more than half of all insured Americans are taking prescription medicines regularly for chronic health problems, according to data compiled last year by Medco Health Solutions. Medco examined prescription records from 2001 to 2007 of a representative sample of 2.5 million customers, from newborns to the elderly. The analysis revealed "that last year, 51 percent of American children and adults were taking one or more prescription drugs for a chronic condition, up from 50 percent the previous four years, and 47 percent in 2001."
The most widely used drugs are those to lower high blood pressure and cholesterol -- problems often linked to heart disease, obesity and diabetes.
Experts say the data reflect not just worsening public health but better medicines for chronic conditions and more aggressive treatment by doctors. Additionally, there is the pharmaceutical industry's relentless advertising.
Americans buy much more medicine per person than any other country. But it was unclear how their prescriptions compare to those of insured people elsewhere. Comparable data were not available for Europe, for instance.
Dr. Robert Epstein, chief medical officer at Franklin Lakes, N.J.-based Medco, said, "Honestly, a lot of it is related to obesity," he said. "We've become a couch potato culture (and) it's a lot easier to pop a pill" than to exercise regularly or diet. Epstein noted the biggest jump in use of chronic medications was in the 20- to 44-year-old age group - adults in the prime of life - where it rose 20 percent over the six years. That was mainly due to more use of drugs for depression, diabetes, asthma, attention-deficit disorder and seizures.
Dr. Sidney Wolfe of Public Citizen's Health Research Group blames doctors for not spending the time to help patients lose weight and make other healthy changes before writing a prescription.
Dr. Grout's comment:
This one should trigger all kinds of alarm bells. We eat food "products" with chemicals that are bad for us, then start taking drugs to counteract the effect of a non-nutritious diet. How backwards is that? Many of our patients find that even if they start a healthy detoxification and nutritional program like FirstLine Therapy late, they can come off their drugs because they no longer need them. This is the perfect example of "less is more." And the choice is ours modify our lifestyle and eating habits, or take drugs to counteract the effects. The drugs come with side effects and do not resolve problems at their core. It seems like a pretty obvious decision to me
New asthma inhalers cause problems and cost more
May 2008
Millions of people with asthma and other lung diseases will have to switch inhalers by the end of the year. And for many, the transition will not be smooth.
The new inhalers have a less forceful spray, and less appealing taste, and differ in how they are primed and cleaned. And they cost perhaps three times as much.
The change is mandated by the federal government in response to a ban of most uses of chlorofluorocarbons, or CFCs, which are blamed for eating away the earth's ozone layer. CFCs are used as propellants in many inhalers. The new "CFC-free" inhalers use propellants called HFAs, for hydrofluoroalkanes.
Three of the four new HFA-propelled inahlers still use the drug albuterol.
"What the government failed to do is to mandate anyone to tell patients and physicians this transition was happening," said Nancy Sander, president of the Allergy and Asthma Network Mothers of Asthmatics. "There is no education, no monitoring of patients, no financial assistance to patients who have to pay higher prices for the new drugs."
The cost difference has meant huge gains for drug companies. As people switched to HFA inhalers in 2006 and 2007, sales of all albuterol inhalers jumped from about $500 million to $1.1 billion, according to I.M.S. Health, a health care information company.
Dr. Grout's comment:
So, we have done something good for the planet by reducing CFCs, but we didn't do something good for the human body. The new inhalers still make use of fluorine, so you get some every time you puff. Fluorine displaces iodine, causes the thyroid to function poorly, and is toxic to the lungs.
Politics control EPA analyses of chemical risks
May 2008
Democratic senators accused the Bush administration of injecting politics into the Environmental Protection Agency's assessment of health risks from toxic chemicals, citing a congressional investigation that concluded assessments are being undermined by secrecy and White House involvement.
A Government Accountability Office report said White House demand for broad interagency involvement in EPA's toxic chemical risk assessments is undermining the agency's ability to make timely, science-based conclusions on the cancer risks and other health impacts of many chemicals. John Stephenson, GAO's director of natural resource programs, told the Senate Environment Committee that the White House Office of Management and Budget not only is closely involved in the chemical assessments but "actually dictating which assessments that the EPA can undertake."
"By placing politics before science, the Bush administration is putting the public in harm's way," said Sen. Barbara Boxer, D-Calif., at a hearing into EPA's toxic chemical programs.
Dr. Grout's Comment:
At issue is the EPA's screening of chemicals used in everything from household products to rocket fuel to determine whether they pose serious risk of cancer or other illnesses. Headlines like this are why Diane Rehm of National Public Radio says the public has little faith anymore in the EPA's ability to protect public health.
Do the White House politicians have such in-depth knowledge of chemistry and medicine that they should feel themselves competent to judge which chemicals should be tested and which are sufficiently safe that they do not need to be tested at all??
Yuma girl's autism case spearheads court fight
April 2008
CNN reports that 13-year old Michelle Cedillo of Yuma, Arizona, is at the center of a court case pitting thousands of families of children with autism against the medical establishment.
Theresa and her husband, Mike, say their only child was a happy, engaged toddler who responded to her name, said "mommy" and "daddy" and was otherwise normal until she received a measles, mumps and rubella (MMR) vaccine at 15 months.
They believe the MMR vaccine, combined with a mercury-containing preservative found in that and other vaccines at the time, drastically altered the course of their daughter's development. Within days of receiving the injection as part of the normal course of vaccinations, Michelle suffered from a high fever, persistent vomiting and problems with her digestion. Worse still, her parents say, Michelle stopped speaking and no longer responded to her name.
Dr. Paul Offit, chief of infectious diseases at the Children's Hospital of Philadelphia, Pennsylvania, says the connection between vaccines and autism is nothing more than a sad coincidence.
"About 20 percent of children with autism will regress between their first and second birthday," says Offit. "So statistically, it will have to happen where some children will get a vaccine. They will have been fine. They will get the vaccine, and they will not be fine anymore. And I think parents can reasonably ask the question, 'Is it the vaccine that did this?'"
The answer is no, according to the CDC, the World Health Organization, and the Institute of Medicine.
Michelle Cedillo's parents disagree. They've sued the government through the National Vaccine Injury Compensation Program, established in 1988 to pay damages to those who have suffered as a result of vaccines. Funded by a 75-cent tax added to the cost of each vaccine dose, the program's trust fund balance is more than $2.7 billion.
Michelle's autism claim is one of 4,900 in a single case before a special federal court, dubbed the "vaccine court," part of the U.S. Court of Federal Claims. The court picked Michelle's claim as the first of a total of nine test cases from the 4,900.
At Michelle Cedillo's hearing last year, Dr. Marcel Kinsbourne, a pediatric neurologist who is a professor at The New School in New York, testified that he thought the measles vaccine was a "substantial factor" in causing the girl's autism. Traces of the measles virus were found in Michelle's gut, leading the Oxford University-trained doctor to conclude the girl's immune system had not rejected the virus. Kinsbourne told the court the measles virus invaded cells in Michelle's brain, resulting in her autism.
Dr. Grout's Comment:
What the CNN story did not reveal was Dr. Paul Offit's conflicts of interest. He is one of the patent holders of the rotavirus vaccine, the recipient of a $350,000 grant from Merck for its development, a consultant to Merck Pharmaceuticals, and a vocal spokesman for the pro-vaccine forces.
Although mercury has been removed from most vaccines, vaccines can still contain traces of mercury, at a level so low the actual amount doesn't have to be stated. In other words, they are called "mercury-free." Also, there has been no attempt to remove the other ingredients in vaccines that can cause neurological damage such as aluminum, formaldehyde, phenol, and MSG (used as a stabilizer).
Alzheimer's Risk Test identify the gene
April 2008
A Pennsylvania company is about to go to market with a genetic test that will tell healthy people whether they are at increased risk for developing Alzheimer's disease. But the test is getting a mixed response from researchers.
The test will be offered by Smart Genetics. For $399, healthy people will give a saliva sample and learn whether they have a risk of Alzheimer's that's 3 to 15 times higher than normal. The analysis is based on variations in the APOE gene, which is widely agreed to play a role in Alzheimer's risk and heart disease.
Researchers express reservations about making the gene test widely available. They worry about the mental health consequences of telling people they may get a disease that's neither preventable nor treatable and is invariably fatal. "I think the benefits [of knowing your genotype] are trivial" and don't justify the emotional risks, says law professor Henry Greely of Stanford University in Palo Alto, California, who in 1997 co-chaired a working group on Alzheimer's genetic testing. The group concluded that genetic testing for Alzheimer's "is not appropriate for most people."
Greely thinks knowing the results might help the roughly 2% of the population with the worst APOE combination: two copies of the deleterious E4 allele, which together confer a roughly 15 times increased risk of the disease. For them, Greely says, the risk is so great that the information may be useful in planning health care needs or retirement.
But a much larger portion of the population, about 25%, carries one copy of APOE4; their risk of Alzheimer's is roughly three times higher than normal. Greely doesn't think these people need to know their APOE status, and Allen Roses of Duke University in Durham, North Carolina, who found the APOE-Alzheimer's link, agrees: "It isn't helpful if there's nothing you can do about it" medically.
But Richard Watson, chief technical officer of Smart Genetics, argues that knowing one is at higher risk can trigger practical responses. Watson says these might include regular memory screenings or making certain financial decisions such as buying long-term care insurance.
Dr. Grout's comment:
What disappoints me about this news article is its fatalistic overtones. Have we somehow missed hearing about the positive roles of Vitamin B12 and B3, and somehow ignored the negative effects of gluten, artificial sweeteners and colorings, chemicals and the like? I must have missed something in the last 15 years when all these things were being discussed and debated in more advanced medical circles. This article merely speaks to predicting and managing a disease.
The Chinese use chess to help stimulate the brain. Chess, of all the possible games, utilizes strategy and planning both activities which originate in the frontal lobes of the brain. There is treatment for memory loss. Stay tuned, on this website, for news of a simple way to stimulate the frontal lobes of the brain to improve memory and concentration no drugs, no bad side effects, just increased mental clarity and memory. This therapy will be available at The Arizona Center for Advanced Medicine starting in July of 2008 the only place in the country for this particular kind of therapy in a medical setting.
Study suggests life expectancy declining
April 2008
Until recently, life expectancy had declined in only two instances in the last century: In sub Saharan Africa because of HIV-AIDS, and in the former Soviet Union, when the healthcare system there collapsed.
But now, it's happening here in the United States, according to a study published in the Apr. 22 issue of PLoS Medicine.
Nearly one-fifth of women in this country had their life expectancy fall, or stay the same between 1961 and 1999, compared with just four percent of males.
Scientists at the Harvard School of Public Health and the University of Washington found the majority of the counties that had the worst downward swings in life expectancy were in the Deep South, along the Mississippi River, and in Appalachia, extending into the southern portion of the Midwest and into Texas.
Researchers examined data from more than 2,000 county 'units' between 1959 and 2001. The found that in about "1,000 of those counties -- mainly poor, rural areas -- life expectancy for women dropped starting in the 1980s, 'primarily because of chronic diseases related to smoking, overweight and obesity, and high blood pressure."
The study also showed "increased death rates among women from lung cancer and emphysema, which probably reflects the fact that American women did not take up smoking in large numbers until tobacco companies started marketing cigarette brands for them in the 1970s."
Dr. Grout's comment:
Could it be that our toxic world - our growing body burden of environmental exposures - is coming back to bite us?
Children taking AD/HD drugs should be screened
April 2008
Children should be screened for heart problems with an electrocardiogram before getting drugs like Ritalin to treat hyperactivity and attention-deficit disorder, according to a new American Heart Association recommendation published online in the journal Circulation.
Stimulant drugs can increase blood pressure and heart rate. For children with heart conditions, the drugs could make them more vulnerable to sudden cardiac arrest an erratic heartbeat that causes the heart to stop pumping blood through the body and other heart problems.
Data indicate that more than two dozen children taking stimulant drugs died suddenly between 1992 and 2005, prompting U.S. regulators to ask for warnings on all the drugs.
About 2.5 million American children and 1.5 million adults take medication for attention-deficit hyperactivity disorder, or AD/HD, according to government estimates. Stimulant drugs, like Ritalin, Adderall and Concerta, are given to help children with AD/HD stay focused and control their behavior.
But Dr. Steven Pliszka, a child psychiatrist at the University of Texas in San Antonio, said he was baffled by the EKG recommendation. He said there's no evidence that sudden death is a bigger problem for children taking stimulants than for children who aren't taking the drugs.
He noted that the heart association doesn't recommended EKG screening for young athletes to prevent sudden death. The group has said it wasn't feasible or cost-effective to screen all student athletes.
Representatives for Shire PLC, which makes Adderall and two other AD/HD treatments, and Norvartis Pharmaceuticals Corp., which makes Ritalin, said the labeling already suggests patients be evaluated for heart problems and an EKG done if needed.
"There's no new information here. And frankly, we're a little perplexed as to the purpose of the American Heart Assocation coming out with this statement at this time," said Shire spokesman Matt Cabrey.
Dr. Grout's comment:
And we are STILL recommending drugs as first-line therapy for AD/HD? What is wrong with this picture? Diet and lifestyle and brain training are more effective, less dangerous, and much healthier.
BOTOX may get to the brain after all
April 2008
Newsweek's Sharon Begley reports that researchers have discovered, after millions of people have used BOTOX, that the botulinum toxin can travel along neurons from the injection site into the brain, at least in lab animals.
Researchers at Italy's Institute of Neuroscience injected rats and mice with botulinum neurotoxin A in doses comparable to those used in people. They report this month in The Journal of Neuroscience that within three days, the toxin had migrated from the whisker muscles to the brainstem, where it disrupted neuronal activity. "The discovery was quite serendipitous ... and surprising," Matteo Caleo, who led the study, told the journal Science. "A significant portion of the toxin is active where it's not intended to be."
That stands in contrast to the findings of earlier studies, which suggested the neurotoxin is completely broken down at the injection site into innocuous compounds and does not migrate beyond itor if it does, only into the bloodstream or lymph system.
Botox's manufacturer, Allergan, said the older studies are more credible.
Begley wrote: "Something else that can be seen in a different light is the hospitalizations and deaths that have been reported following Botox injections. In 2005 scientists at the FDA analyzed 1,437 such "adverse events" between 1989, when Botox was approved for eye spasms, and 2003. Most came from people who got Botox to erase their wrinkles, but the 28 deaths occurred in people who had received it for medical purposes. The FDA didn't do much in response, but since then it has been getting new reports of serious adverse reactions in people receiving Botox, and launched a safety review."
Dr. Grout's Comment:
So
one more reason to be wary of trying to appear to be something other than what we actually are. Health and beauty come through good nutrition for body, brain and mind. If we are content with the current state of our lives, there is no reason for frown lines, and they do not have to be flattened by artificial means. Botox is a drug in fact it is a deadly toxic byproduct of the botulinus bacterium which used to be found in inadequately sterilized canned goods. Why would we want to inject deadly toxins deliberately into our bodies?
Plastic's bisphenol A is a gender-bender
April 2008
A new government report's findings on rat studies suggest a chemical used to make plastic baby bottles and shatterproof containers is linked to a range of hormonal and cancerous problems.
The federal National Toxicology Program said Tuesday that experiments on rats found precancerous tumors, urinary tract problems and early puberty when the animals were fed or injected with low doses of the plastics chemical bisphenol A.
More than 90 percent of Americans are exposed to trace amounts of bisphenol, according to the CDC. The chemical leaches out of water bottles, the lining of cans and other items made with it.
While animal studies only provide "limited evidence" of bisphenol's developmental risks, the draft report stresses the possible effects on humans "cannot be dismissed." The group is made up of scientists from the Centers for Disease Control, the Food and Drug Administration and the Institutes of Health.
However, the American Chemistry Council, which represents manufacturers, said the report "affirms that there are no serious or high level concerns for adverse effects of bisphenol on human reproduction and development." Among the manufacturers of bisphenol are Dow Chemical Co. and BASF Group.
The FDA in November said there is "no reason at this time to ban or otherwise restrict its use." The agency on Tuesday did not immediately have any comment about the new report.
Rep. John Dingell, D-Mich., called on FDA Tuesday to reconsider the safety of bisphenol, saying the toxicology report's findings "fly in the face of the FDA's determination."
Earlier this month state lawmakers in New Jersey passed a bill that would ban the sale of all products containing bisphenol.
Dr. Grout's Comment:
Canada has now banned the sale of products containing bisphenol A. WalMart Canada pulled off the shelves baby bottles containing this toxic chemical. Interestingly, this did not happen in the United States. WalMart declared its intention to remove those products by early 2009. In the meantime, the products are still on the shelf. This reminds me of the thimerosal story in 1999 thimerosal was banned from vaccines as a preservative, but it was still permitted to sell the vaccines left over from the old manufacturing ways and so thimerosal did not actually come out of the supply chain until about 2002, when the old stores were finally used up. It is possible that there is a conflict of interest between our physical health and the financial health of big industry?
Earlier studies showed low amounts of bisphenol A have the ability to mimic human estrogen, but now we see a U.S. government study addressing the problem.
The draft report said, in pretty plain language, that "bisphenol A can migrate into food from food and beverage containers with internal epoxy resin coatings and from consumer products made of polycarbonate plastic such as baby bottles, tableware, food containers, and water bottles.
Bisphenol A can also be found in breast milk. Biomonitoring studies show that human exposure to bisphenol A is widespread."
The report said that "laboratory rodents show that exposure to high dose levels of bisphenol A during pregnancy and/or lactation can reduce survival, birth weight, and growth of offspring early in life, and delay the onset of puberty in males and females.
A variety of effects related to neural and behavior alterations, precancerous lesions in the prostate and mammary glands, altered prostate gland and urinary tract development, and early onset of puberty in females have been reported in laboratory rodents exposed during development to much lower doses of bisphenol A that are more similar to human exposures."
Do you carry a polycarbonate water bottle your car in the Arizona summer heat? If so, then you'll find this part of the report interesting: "The degree to which bisphenol A migrates from polycarbonate containers into liquid appears to depend more on the temperature of the liquid than the age of the container, i.e., more migration with higher temperatures."
Environmental Working Group found that bisphenol A leaches from the metal lining of cans and has been found at alarmingly high rates in one-third of the cans of baby formula tested. Bisphenol A is also found in soda cans, in refrigerator shelving, microwave ovenware, water pipes, electrical appliances, flooring, and part of the plastic used in covering children cavities.
You can join the growing ranks of consumers who are demanding glass a good idea for health and for the environment because glass can be recycled. Plastic will be around for tens of thousands of years.
Bats are dying like bees, it's a mystery
April 2008
Something is killing the bats. And as was the case with the bees a couple years ago, no one knows for sure what.
The epicenter of the annihilation so far is New York. Hikers noticed dead and dying bats littered outside the caves where they hibernate. Bats normally hybernate during the winter and do not fly during the daytime. The bats are also noted to be hibernating close the caves' entrances, in contrast with their usual inclination to go deeper inside.
The loss of bats cascaded this winter to the point researchers fear extinction is underway.
The cause is unknown, though there is a name for the phenomenon, White Nose Syndrome. It's a fungus that's particularly obvious on the nose and face, though it's found dotted all over the bats' bodies. It is believed to be just a symptom of an underlying problem, as yet unknown.
A primary suspicion is the use of pesticides. The fact that there has been wide spread spraying of pesticides for West Nile Virus is a possibility.
The president of Bat Conservation International, Merlin Tuttle, stated, "So far as we can tell at this point, this may be the most serious threat to North American bats we've experienced in recorded history."
A wildlife biologist with Vermont's Fish and Wildlife Department, Scott Darling says, "Logic dictates when you are potentially losing as many as a half a million bats in this region, there are going to be ramifications for insect abundance in the coming summer." Translation: massive mosquito outbreaks.
Crops also may be affected. Bats are significant controllers of many crop-destructive insects.
Dr. Grout's Comment:
The loss of bats may be an even worse concern than the loss of bees. Bats are the world's greatest insect eaters. A small brown bat can eat as many as 600 mosquitoes in an hour. The implications for agriculture are enormous. The spread of severe communicable diseases could be devastating. Diseases borne by mosquitoes include Eastern Equine Encephalitis, Malaria, Dengue Fever, and West Nile Virus.
Health Insurance Mafia by Jonathan Kellerman
April 2008
Writing in the Wall Street Journal 4-14-08, author Jonathan Kellerman points out that most discussions about the rising cost of health care emphasize the need to get more people insured. Excerpt:
"But perhaps the solution to much of what currently plagues us in health care rests on a radically different approach: fewer people insured.
"Any middleman interposed between seller and buyer raises the price of a given service or product.
"Insurance is all about betting against negative consequences and the insurance business model is unique in that profits depend upon goods and services not being provided. Using actuarial tables, insurers place their bets.
"Health insurers suck the lifeblood out of the supply chain with obstructive strategies. For that reason, there will be progressively draconian rationing using denial of authorization and steadily rising co-payments on the patient end; massive paperwork and other bureaucratic hurdles, and steadily diminishing fee-recovery on the doctor end.
"Some of us are old enough to remember visiting the doctor and paying him/her directly by check or cash. The same went for hospitals: no $20 aspirins due to insurance-company delay tactics and other shenanigans.
"A hefty proportion of health-care services office visits, minor surgeries would be affordable to most Americans if the slice of the health-care dollar that currently ends up in the coffers of insurance companies was eliminated. It is a fantasy that 'insurance is paying.' It isn't. There is no free lunch and no free physical exam.
"If substantial numbers of health-care providers shook off the insurance monkey on their back, en masse, and the supply of providers was substantially increased by opening more medical schools, the result would be a more honest, cost-effective system benefiting everyone. Except the insurance companies.
Dr. Kellerman, clinical professor of pediatrics and psychology at USC's Keck School of Medicine, is the author of numerous crime novels and three books on psychology. His latest novel is "Compulsion" (Ballantine, 2008).
Dr. Grout's comment:
Right on, Dr. Kellerman! I could not have said it better myself. The assumption seems to be that insurance rather than the service delivered by doctor to patient is the more important element in the equation.
Low birth weight, excessive adolescent weight is it low-grade inflammation?
April 2008
According to a study published in the European Heart Journal, "small size at birth, and excessive weight gain during adolescence and young adulthood, may lead to low-grade inflammation."
Paul Elliott, Ph.D., of Imperial College London, and colleagues, analyzed data on 5,840 people who were followed from birth to the age of 31. Researchers looked at the participants' levels of C-reactive protein (CRP) in their blood. Elevated levels of CRP can indicate a chronic, low-grade inflammation. The authors "found that those who were amongst the smallest at birth, but who then put on the most weight by age 31, had the highest average CRP levels."
The rapidity of growth in adolescence appeared to be more important for inflammation than weight or BMI [body mass index] alone. The researchers wrote, "The finding that weight gain from adolescence to young adulthood appears to play a greater role in low-grade inflammation than weight in adolescence per se, could have important implications for the primordial prevention of cardiovascular disease."
Dr. Grout's Comment:
All the more reason to start our children out with very healthy anti-inflammatory foods meats, fruits and vegetables without additives or colorings or extra sugars. We could almost certainly prevent most of the healthcare spending in later life if we gave our children a good start in life, with food messages to their genes which promote health.
Normal body weight may have high body fat - increased disease risks
April 2008
More than half of U.S. adults of normal body weight may have high body fat, and may be at risk for disease, according to findings presented at the American College of Cardiology meeting in Chicago.
The study specifically links so-called normal-weight obesity with risk factors like high blood cholesterol and metabolic syndrome. Moreover, those who fell "within a healthy weight range for their height a body mass index range of 18.5 to 24.9," were also "more likely to have risk factors for heart disease, hypertension, and diabetes."
Researchers at the Mayo Clinic in Rochester, Minn., collected data on 2,127 people who participated in the U.S. government's Third National Health and Nutrition Examination Survey, and found that "61 percent of the participants had levels of body fat that indicated 'normal weight obesity." In addition, the team noted "changes in blood chemistry that can affect heart and metabolic health, including high cholesterol" and "high levels of leptin, a hormone found in fat and other tissues that's involved in appetite regulation."
Dr. Grout's Comment:
This is called "sarcopenic obesity" meaning relative lack of muscle compared with total body weight. This is where measurement of the bio-impedance analysis (BIA) of the body is helpful, to gauge amount of body fat, muscle, intracellular water, and other parameters which help us to gauge how healthy or toxic a person may be. At the Arizona Center for Advanced Medicine we do this measurement on all our new patients, and then repeat the measurement periodically as they go through our nutritional program which is geared at restoring the body to health and eliminating the risk factors of hypertension, hyperglycemia, high cholesterol and metabolic syndrome.
Mercury fillings banned - Norway and Sweden are first
April 2008
According to the Journal of the American Dental Association, effective April 1st, 2008, Sweden banned mercury fillings. Norway banned them effective January 1, 2008. Other countries are contemplating similar moves.
The American Dental Association is not on board. "Banning 'dental amalgam' is a political issue that will not only have no impact on total worldwide mercury pollution, but also removes a viable treatment option for dentists and their patients," argues Derek Jones in an editorial published in the Journal of Dental Research.
"These bans clearly indicate that amalgam is no longer needed. There are viable non-mercury filling substitutes that are used everyday in the U.S.," said Michael Bender of the U.S. Mercury Policy Project. "By eliminating amalgam use, which is 50% mercury, we can reduce mercury pollution much more efficiently than end-of-the-pipeline solutions."
Dr. Grout's Comment:
Dental amalgam, or silver filling material, has been around for some 150 years. Yes, it's the same mercury you saw in thermometers as a kid and were warned never to touch. Mercury is a known toxin. From a dentist's perspective, it is a long-lasting material that is cheap and easy to use. It is estimated that half of all dentists still use mercury-based restorations in their practice.
Consumers for Dental Choice, a non-profit organization, is suing the FDA, asking it to remove mercury fillings from the market. Mercury isn't the only culprit by the way, lots of metals used in amalgam filings that can affect certain individuals with a particular sensitivity. The mouth is part of the overall body and it can infect the rest of the body. If you think you have a problem component in your fillings, we can test you for an allergic or hypersensitivity reaction, just as we can test for any other allergic reaction like pollens or molds.
Measles reported in Pima County call for vaccinations
April 2008
The Arizona Republic reports that nine cases of measles have been confirmed in Pima County since February.
Four adults and four children have been infected. Officials say it could have spread out of Pima County.
"One case of the measles in a community is an outbreak," Dr. Karen Lewis, a medical director with the Arizona Department of Health Services, said. "You don't know how well people are immunized or not immunized until you have one case."
Most children are now immunized against the measles, and many adults born before 1957 had a case of the "hard measles" when they were young and are now immune, Lewis said.
But health officials are concerned about a trend against vaccinating children, which Lewis said is born out of a belief in vaccines' links to other problems, like autism. She said studies have shown no such link.
The disease is spread in the air, and people can become infected just by being in the same room or in a room with the same ventilation as someone infected. The first few Pima County patients were people exposed in the emergency room of Northwest Medical Center, where a woman from Switzerland was waiting to be seen.
The Tucson outbreak follows one in San Diego last month in which 12 children were infected. That outbreak is believed to have been caused by a child who contracted the disease while visiting Switzerland, which has been experiencing a large measles outbreak.
Dr. Grout's Comment:
Let us ask, "What would be the harm in getting the measles?" A vaccine only protects a child for about 8 years; an actual case of measles confers protection for life. Measles in adults is much more serious.
In the factual world of public health risk assessment, 1 in 1000 children who contracts measles dies or gets encephalitis, the other 999 are protected for life. That's 0.1% serious or fatal complications.
We now have an autism epidemic where we are seeing 1 in 150 children affected. That's a big incidence possibly from complications of vaccination. Lewis may say, "studies show no link" but that is not accurate. In November last year, after years of insisting there is no evidence to link vaccines with the onset of autism spectrum disorder (ASD), the US government quietly conceded a vaccine-autism case in the Court of Federal Claims.
In many autistic children the MMR vaccine with live measles virus has produced an ongoing intestinal infection. Live viruses can trigger a strong and long-lasting immunity, but they may cause serious infections and even death in people who are immune-compromised and sometimes may cause serious infections in people who are apparently healthy.
Parents need to weigh the risk.
Cell phones more dangerous than smoking
March 2008
Mobile phones could kill far more people than smoking or asbestos, a study by an award-winning cancer expert has concluded. He says people should avoid using them wherever possible and that governments and the mobile phone industry must take "immediate steps" to reduce exposure to their radiation.
The study, by Dr Vini Khurana, draws on growing evidence that using handsets for 10 years or more can double the risk of brain cancer. Cancers take at least a decade to develop, invalidating official safety assurances based on earlier studies which included few, if any, people who had used the phones for that long.
"It is anticipated that this danger has far broader public health ramifications than asbestos and smoking," says Professor Khurana. His assessment is partly based on the fact that three billion people now use the phones worldwide, three times as many as smoke. Smoking kills some five million worldwide each year.
Earlier this year, the French government warned against the use of mobile phones, especially by children. Germany also advises its people to minimize handset use, and the European Environment Agency has called for exposures to be reduced.
Professor Khurana a top neurosurgeon who has received 14 awards over the past 16 years, has published more than three dozen scientific papers reviewed more than 100 studies on the effects of mobile phones. He has put the results on a brain surgery website, and a paper based on the research is currently being peer-reviewed for publication in a scientific journal.
Dr. Grout's Comment:
A mobile-phone industry group dismissed Khurana's claims as exaggerated and pointed out that health groups say cell phones are safe. The American Cancer Society also says there is no link.
But consider this: It took until the 1960's for people to accept the idea that cigarette smoke was harmful. It was another 20 to 30 years before secondhand smoke was accepted as dangerous and outlawed in the work place. Cigarette proponents for decades offered that health claims were exaggerated, that "It's not for sure," and "It needs more study."
Resveratrol and pancreatic cancer helpful antioxidant
March 2008
Resveratrol, an antioxidant found in red-purple grape skins and red wine, "destroyed pancreatic cancer cells," according to a study published in Advances in Experimental Medicine and Biology.
Paul Okunieff, M.D., chief of radiation oncology at the University of Rochester Medical Center in New York, and colleagues, examined the effects of a 50 microgram/milliliter dose of resveratrol on pancreatic cancer cells alone, and in combination with radiation treatment. Researchers found that "resveratrol seems to have a therapeutic gain by making tumor cells more sensitive to radiation and making normal tissue less sensitive." Moreover, resveratrol "injured the cancer cell's energy source, and decreased its potential to function." The authors concluded, "While additional studies are needed, this research indicates that resveratrol has a promising future as part of the treatment for cancer."
Dr. Grout's comment:
It is good to see appearing in mainstream literature what has been common knowledge in functional medicine circles for years. Yes, anti-oxidants are very helpful to treat all forms of oxidative stress, including cancer. Resveratrol is one of the polyphenol antioxidants abundant in grapes, berries, tea, red cabbage, eggplant, beans, whole grains, and cocoa. It is most abundant in blue, red, and purple grapes. Resveratrol is also abundant in a Chinese medicinal root called hu zhang (Polygonum cuspidatum), which is often the source of resveratrol in dietary supplements.
Resveratrol is produced by the grape plant to protect it against environmental stress. How fitting that it will also help to protect us against environmental stress because what is cancer, if not the ultimate result of environmental stress? And when we eat the grapes, we derive the same benefit as the plant this is called xenohormesis messages through our food from other species. How much better to eat these helpful messages, rather than the terrified hormonal messages from the modern meat slaughterhouses.
WalMart goes rBGH free cleaner milk
March 2008
WalMart announced its store brand of milk, which is labeled "Great Value," will no longer come from cows injected with Monsanto's controversial genetically engineered hormone, rBGH/rBST.
rBGH is banned in Europe, Canada, and most of the industrialized world.
WalMart said its change was prompted by consumer demands. "Many WalMart customers have expressed a desire for milk choices," the company said in a news release.
Organic Consumer Union's Director, Ronnie Cummins, stated in an interview with the Toronto Globe and Mail, Wal-Mart's announcement will likely serve as a tipping point for driving Monsanto's controversial bovine drug off the market. The group has campaigned aggressively against rBGH. According to Cummins, "After 14 years of bullying consumers and buying off FDA and USDA bureaucrats, this is the beginning of the end for this dangerous drug."
Dr. Grout's Comment:
rBGH is sold as Posilac. Monsanto has been forced to admit to about 20 toxic effects, including mastitis, on its Posilac label. Mastitis causes increased amounts of pus in milk. The use of it increases the amount of milk cows give.
According to Dr. Samuel Epstein, rBGH milk is supercharged with high levels of a natural growth factor (IGF-1), which is readily absorbed through the gut. Excess levels of IGF-1 have been incriminated as a cause of breast, colon, and prostate cancers; IGF-1 blocks natural defense mechanisms against early submicroscopic cancers.
WalMart's move sends a powerful signal to food manufacturers about the growing mainstream demand for food that is free of hormones and other man-made contaminants. Educated consumers have the power to move mountains.
Dennis Quaid's twins drug ordeal hospital mistakes
March 2008
Actor Dennis Quaid and his wife, Kimberly, were featured on the news program 60 Minutes as they kicked off a new campaign to bring national attention to hospital errors.
When the Quaid's newborn twins showed signs of a having a staph infection last November, they were admitted to Cedars-Sinai Hospital in Los Angeles for treatment. A hospital mistake resulted in two massive overdoses of a blood thinner that caused the babies to nearly bleed to death.
The same type of avoidable mistake was made a year earlier in an Indiana hospital. In that case, six infants were given multiple adults doses of heparin instead of the pediatric version. Three of the six infants died.
"The mistakes that occurred to us were not unique," Quaid said. Preventable human medical error is one of the leading causes of death in America. "It's bigger than AIDS. It's bigger than breast cancer. It's bigger than automobile accidents. And, yet, no one seems to be really be aware of the problem," he says.
Dr. Grout's Comment:
In 2000 the Institute of Medicine (medical arm of the National Academy of Science) published the results of a long term study on medical errors titled "To Err is Human".
Among its findings-
Every single year in the US direct medical errors result in:
- at least 100,000 deaths (half medication error, half surgical error)
- 116 million extra doctors visits
- 77 million extra prescriptions
- 17 million extra emergency room visits
- 8 million extra hospitalizations
Another 225,000 deaths occur from preventable adverse events such as hospital borne infections.
It is estimated that only 5 to 20 percent of adverse reactions and medical mistakes are ever reported.
The "To Err is Human" report concluded that if put in their own category, medical errors would be the 5th leading cause of death in the US killing more people than stroke, Alzheimer's, most forms of cancer, and car accidents.
According to Dr. Carolyn Dean, author of Death by Modern Medicine in 2005, the mainstream medical industry kills 784,000 people each year in America; "Saddam Hussein did not kill that many people each year," she wrote.
Genes factor into post-traumatic stress disorder child abuse key
March 2008
According to a study published in the March 19th issue of the Journal of the American Medical Association, "people abused as children, who have variations of a gene related to stress, may be at higher risk of post-traumatic stress disorder (PTSD) later."
Elizabeth B. Binder, M.D., Ph.D., of Emory University in Atlanta, Ga., and colleagues, recruited 900 participants from the general medical and obstetrics/gynecology clinics of a public hospital. The patients "reported a history of child-abuse trauma or trauma from other causes on a survey," and they all "had single-nucleotide polymorphism genotyping."
The researchers analyzed eight FKBP5 polymorphisms, and found no significant effect on the total PSS [PTSD Symptom Scale] score, and no significant interaction with exposure to nonchild abuse trauma. But, analysis identified four SNPs [single nucleotide polymorphisms] that showed significant interactions with childhood abuse. Moreover, "SNPs associated with the highest induction of FKBP5 expression were associated with increased risk of adult PTSD symptoms, and greater GR [glucocorticoid receptor] sensitivity."
Dr. Grout's comment:
Lots of genetic variants can certainly explain in part why some people get a disease and others don't, with exactly the same predisposing factors. However, it is important to realize that there still has to be a "provoking incident" in order for the genetic variant to result in an actual expression of disease. This is called an "epigenetic" factor, something which happens to the person with the genetic variant. So
genetic variants exist. They do not result in disease unless the epigenetic factors are sufficient to overwhelm the system. Thus, post traumatic stress disorder does not occur in the absence of a significant traumatic stress. Heart disease and osteoporosis do not occur in the absence of a diet and lifestyle predisposing to inflammation. We can't change our genetic variants, but we certainly have a great deal of influence over their expression.
Not all diabetes is the same there are genetic subtypes
March 2008
The Associated Press reports, "Diabetes is undergoing a genetics revolution that suggests there actually are many subtypes of the disease." A set of subtypes is called MODY, which is "shorthand for six different subtypes thought to account for two percent of all diabetes." In addition, each is caused by a single, different gene. Diabetes specialists typically suspect MODY "when patients are extra hard to treat, especially skinny people diagnosed with Type 2 diabetes, or young adults with diabetic relatives who abruptly seem to develop Type 1."
Andrew Hattersley, M.D., a British physician-scientist, has pioneered how to treat single-gene subtypes. For instance, Dr. Hattersley has found that old diabetes drugs called sulfonylureas neutralize a gene called HNF1-alpha so insulim production resumes. To date, researchers have discovered 16 genes that "play a role in Type 2 diabetes, and at least 14 in Type 1." MODY may explain at least partially why diabetes strikes one person who's overweight, but not another who's equally heavy, or why one diabetic needs dialysis, while another has healthy kidneys despite decades of bad blood sugar.
Dr. Grout's Comment:
So maybe those people who respond poorly to a low glycemic diet would respond better if they were simultaneously taking something to increase their insulin sensitivity like the hops rho alpha iso acids pioneered by the Metagenics company, or even like metformin, pioneered by the pharmaceutical industry. It is helpful to know the genotype, in order to be able to treat the individual in the most appropriate and economic way.
'Natural' personal care products contain carcinogens misleading
March 2008
The Organic Consumers Association (OCA) reports a toxic chemical linked to cancer is found in more than 40 percent products that call themselves "natural".
OCA analyzed leading "natural" and "organic" brand shampoos, body washes, lotions and other personal care products for the presence of the undisclosed carcinogenic contaminant 1,4-Dioxane, a petroleum compound.
OCA reports, "Ethoxylation, a cheap short-cut companies use to provide mildness to harsh ingredients, requires the use of the cancer-causing petrochemical Ethylene Oxide, which generates 1,4-Dioxane as a by-product. 1,4-Dioxane is considered a chemical 'known to the State of California to cause cancer' under proposition 65, and has no place in 'natural' or 'organic' branded personal care products. 1,4-dioxane is also suspected as a kidney toxicant, neurotoxicant and respiratory toxicant, and is a leading groundwater contaminant."
Some of the leading brands which were found to contain 1,4-dioxane included Jason Pure and Natural Organic, Giovanni Organic Cosmetics, Kiss My Face, and Nature's Gate Organics.
Dr. Grout's Comments:
When reading labels on personal products and makeup, you can avoid ingredients with "myreth," "oleth," "laureth," "ceteareth," any other "eth," "PEG," "polyethylene," "polyethylene glycol," "polyoxyethylene," or "oxynol," in the names.
Consumer beware. Your best bet is to purchase products whose ingredients you can pronounce or are certified under the USDA National Organic Program.
Brazilian protesters destroy GM crops sending a message
March 2008
Approximately 300 women in Brazil burst into a property owned by the US company Monsanto and destroyed a plant nursery and crops containing genetically modified corn.The women were protesting what they saw as environmental damage by the crops.
The Brazilian government had "caved in to pressure from agrobusinesses" by recently allowing tinkered crops to be grown in the country, said Igor Foride, a member of the Landless Workers' Movement.
In Brasilia, a protest by another 400 women from an umbrella group, Via Campesina (the Rural Way), was held in front of the Swiss embassy against Syngenta, a Swiss company that is selling genetically modified seeds in Brazil.
Via Campesina said in a statement that "no scientific studies exist that guarantee that genetically modified crops won't have negative effects on human health and on nature."
Dr. Grout's Comment:
Violence is a tough way to make a point, but their point is valid. There are no studies that show GM foods are safe, but there are studies that raise serious doubts.
Exposure to diacetyl fumes may cause lung damage - "popcorn lung"
March 2008
According to a study published online in Toxicology Sciences, a "chemical used to give butter flavor to popcorn can damage the lungs and airways of mice." Scientists at the National Institute of Environmental Health Sciences studied the effects of diacetyl, a component of artificial butter flavoring on mice.
Daniel Morgan, Ph.D., and colleagues, found that the mice developed lung damage when exposed to levels of diacetyl fumes found in flavoring factories. Other studies have linked diacetyl fumes to a rare, life-threatening lung disease called bronchiolitis obliterans [or popcorn lung] in workers in the flavor industry. The disease makes it difficult for air to flow out of the lungs.
Currently, the FDA classifies diacetyl as being 'generally recognized as safe,' but consumer advocates have petitioned the agency to reconsider "diacetyl's safety status.
Dr. Grout's Comment:
This study speaks for itself. We keep coming back to the same old statement, if we can't pronounce it, and it has to be made in a laboratory, we probably should not eat it (or breathe it).
CDC withdraws preference for combination MMRV increased seizures
March 2008
U.S. health officials are no longer recommending the combination MMRV (measles, mumps, rubella, and varicella) vaccine over the MMR vaccine in combination with a separate varicella vaccine. According to a report published in the Mar. 14 issue of the Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, the move comes after new data showed that the MMRV shot increased the risk for febrile seizures - convulsions brought on by fever - in children aged 12 to 23 months. Another reason for the change is the fact that due to "manufacturing difficulties, the MMRV shot, made by Merck, won't really be available until about this time next year."
The changes have nothing to do with a possible vaccination link to autism," said Dr. Robert Frenck, a professor of pediatrics at Cincinnati Children's Hospital.
Dr. Grout's Comment:
At least this delay gives us time to inform our parents that the vaccination schedule, as it is currently established, is unsafe and needs to be significantly modified in order to be safe for those of our children who have difficulty with detoxification. And is it possible that the recorded drop in IQ scores over the past 10 years may reflect the difficulty of ALL our children with these injections of toxic and infectious compounds? We have an entire lost generation, those children who received vaccinations between 1990 and 2002, who are at risk for developmental and immune system dysfunction for the rest of their lives. If we learn from the events, then we can do something to help future generations of children. It is up to us, one child at a time.
Pharmaceuticals found in drinking water what affect on humans?
March 2007
An Associated Press investigation found that a vast array of pharmaceuticals - including antibiotics, anti-convulsants, mood stabilizers and sex hormones - have been found in the drinking water supplies of 24 major metropolitan areas, from Southern California to Northern New Jersey.
The concentrations of these pharmaceuticals are tiny, measured in quantities of parts per billion or trillion, far below the levels of a medical dose. Utilities insist their water is safe.
Drugs enter the water supply when unused amounts of drugs are excreted into the toilet. And drugs from commercial livestock and pets also enter the water supply after excretion.
While researchers do not yet understand the exact risks from decades of persistent exposure to random combinations of low levels of pharmaceuticals, recent studies have found alarming effects on human cells and wildlife.
"We recognize it is a growing concern and we're taking it very seriously," said Benjamin H. Grumbles, assistant administrator for water at the U.S. Environmental Protection Agency.
The AP's investigation also indicates that watersheds, the natural sources of most of the nation's water supply, also are contaminated. Pharmaceuticals also permeate aquifers deep underground, source of 40 percent of the nation's water supply.
Even users of bottled water and home filtration systems don't necessarily avoid exposure. Bottlers, some of which simply repackage tap water, do not typically treat or test for pharmaceuticals, according to the industry's main trade group. The same goes for the makers of home filtration systems.
Dr. Grout's Comment:
Phoenix's water was not tested as part of this AP investigation. According to the Arizona Republic edition of 03-14-08, both Phoenix and Scottsdale plan to initial testing of their drinking water for pharmaceutical medications. Other cities in the area are choosing to wait and see if the Federal Government tells us that the levels of pharmaceuticals are dangerous. I must confess that I am VERY glad I live in one of the cities which is choosing to be proactive about this potentially extremely dangerous issue.
Recent laboratory research has found that small amounts of medication have affected human embryonic kidney cells, human blood cells and human breast cancer cells. The cancer cells proliferated too quickly; the kidney cells grew too slowly; and the blood cells showed biological activity associated with inflammation.
The federal government doesn't require any testing and hasn't set safety limits for drugs in water. Given the power and influence of the pharmaceutical industry, safety limits if there are such things could be a long time coming.
Give up multivitamins - Harvard warns
February 2008
According to Harvard Men's Health Watch, recent studies have linked multivitamin use to prostate cancer.
"Scientists have many unanswered questions about folic acid and cancer. One popular theory, still unproven, suggests that timing and dose may explain folate's apparently contradictory effects on cancer," researchers said.
Multivitamin/mineral supplements are regularly taken by over one-third of American adults. The news could strike a damaging blow to the multivitamin market if consumers stop buying multivitamins which contain folic acid.
Harvard suggested the average man could give up the multivitamin, at least until scientists solve the puzzle of folic acid and cancer.
They said: "There is no proof that a daily multi vitamin is harmful. Still, it now seems possible that the high levels of folic acid achieved by well-intentioned people who take a multivitamin and eat healthful foods could increase the risk of colorectal and possibly prostate and breast cancers."
Harvard added that if men stop taking a multivitamin, they should consider taking a vitamin D supplement. This is because the typical diet for most men and women does not supply enough of this vitamin, Harvard said.
Dr. Grout's Comment:
There is a key piece of information missing in the news reports: what kind of folic acid is in your supplement? Folate is the water-soluble B vitamin that occurs naturally in food. Folic acid is the synthetic form of folate and a cheap version of it is often found in supplements and added to fortified foods. A third type is methyltetrahydrofolate, (MTHF), the predominant form of folate in cerebrospinal fluid. Low CSF MTHF levels are associated with inborn errors of metabolism affecting folate metabolism and in dietary deficiency of folate.
This vitamin's primary job is to maintain the cells' genetic code, regulate cellular division, and transfer chromosomes form one cell to another. There is some evidence that a deficiency of folate can cause damage to DNA that may lead to cancer.
Folate maintains optimal function of the detoxification pathway and it needs the catalysts vitamins B12, B6 and vitamin C to carry out its functions effectively.
There is evidence that your body can reject synthetics. Even the allopathic community has noted that synthetic vitamin E is a poor substitute for the real thing and does little to boost your health. But the debate is unsettled about synthetic folic acid. According to Aileen Burford-Mason, president of the Holistic Health Research Foundation of Canada, "some people genetically are not equipped to cleave the folate out of food and convert it to folic acid. It's only well utilized by about 70 per cent of the population. But there is a synthetic form called methyltetrahydrofolate that 100 per cent of people can use."
Vitamins in isolation, without any knowledge of what else is going on in the system, may not be totally harmless. It is possible that DNA may be turned on (or off) by methyl groups (which folic acid supplies). If the rest of the system is unhealthy, or contains multiple foods/chemicals/drugs which are carcinogenic, then perhaps indeed there may be an association between turning off some DNA and getting cancer. It's actually the old "post hoc ergo propter hoc" argument because B follows A, that does not necessarily mean than A causes B B may in fact be caused by some as yet unmeasured C or D that we haven't considered. I think the Harvard study is making unwarranted conclusions.
FDA approves Nexium for kids aged 1-11 years old
February 2008
The FDA has approved use of the drug Nexium (esomeprazole magnesium) manufactured by AstraZeneca, in children aged one to 11 who have gastroesophageal reflux disease (GERD). The agency "approved liquid and delayed-release capsules of Nexium in doses of 10 milligrams or 20 milligrams for these youngsters." Nexium is part of a class of drugs known as proton pump inhibitors that decrease the amount of acid produced in the stomach, and help heal erosion in the lining of the esophagus."
The FDA's "approval was based on an extrapolation of data from adult studies as well as safety and pharmacokinetic studies performed in pediatric patients.
Common side effects of the drug when used in this age group included "headache, diarrhea, abdominal pain, nausea, gas, constipation, dry mouth, and fatigue."
Dr. Grout's comment:
Are we completely insane??? One year old? Nexium? Esomeprazole works by blocking acid production in the stomach. GERD is a condition in which backward flow of acid from the stomach causes heartburn and injury of the esophagus. I remember we were taught in medical school how dangerous these drugs are. Now the FDA is recommending that instead of teaching mothers how to feed their children properly, we just feed youngsters a purple pill to shut down the stomach's natural ability to produce acid to digest food.
I am always glad to see that people can still figure things out though. Here's what one post on medheadlines.com had to say:
"Whenever my daughter has acid reflux, I give her 1 teaspoon of apple cider vinegar. It works instantly. Our nation is drugged from cradle to grave by harmful pharmaceutical drugs. We've become a nation of drug addicts, and many have died as a result (e.g. Heath Ledger). How ignorant of all of us to believe that every ailment imaginable can be fixed with a pill
"
Combo vaccine linked to seizures, fever chickenpox and MMR
February 2008
According to data presented to the meeting of the Advisory Committee on Immunization Practices, children suffered higher rates of fever-related convulsions when they got a Merck & Co. combination vaccine instead of two separate shots. Specifically, the Centers for Disease Control and Prevention-funded study found that for "children ages 12 months through 23 months, the rate of seizures was twice as high in toddlers who got ProQuad, compared with those who got one shot for chickenpox, and one for the three other diseases:" measles, mumps, and rubella.
Merck officials said there was five times more chickenpox antigen, the key ingredient, in the vaccine than in the stand-alone chickenpox shot. But, it remains to be seen if that explains the seizure phenomenon. Although the federal panel "had previously taken a position that they preferred doctors give children as few needle sticks as possible," this finding has prompted them "to water down their preference for the combo vaccine."
Dr. Grout's comment:
Shall parents decide between one more unnecessary shot, or seizures? Absurd choices. I for one do not recommend giving children the MMR vaccine at all.
CDC says annual flu vaccine is for children - aged six months to 18 years
February 2008
NBC Nightly News reported that although "this year's flu vaccine doesn't work all that well, a federal panel came out with a broad new recommendation about flu vaccines."
The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practice "wants every child from six months to eighteen years, to get a flu shot [each year], starting with the 2009 flu season."
Currently, the CDC recommends the flu shot for children five and under. But, this new recommendation could change that drastically. The Los Angeles Times points out that an estimated 30 million more children would be vaccinated. While the shots would not be mandatory, "the federal imprimatur would make physicians more likely to offer the vaccine to children."
In making the recommendation, the panel sought "to reduce both the time children and parents lose from visits to pediatricians and missing school, and the need for antibiotics for complications. The CDC expects that the vaccine industry, which made 132 million doses available this year, will be able to produce a sufficient supply in future years. If the CDC adopts the panel's recommendation, it would be one of the largest expansions in flu vaccination coverage in U.S. history."
While many healthcare professionals and parents applauded the panel's recommendation, others criticized it. Rita Shreffler, executive director of the National Autism Association, stated, "The CDC continues to minimize the dangers of injecting mercury and aluminum into our kids."
Dr. Grout's comment:
So maybe if we give the dysfunctional vaccine more often it will work better?
Government Concedes 1st Vaccine-Autism Case in Court - Now What?
February 2008
After years of insisting there is no evidence to link vaccines with the onset of autism spectrum disorder (ASD), the US government has quietly conceded a vaccine-autism case in the Court of Federal Claims. The unprecedented concession was filed on November 9, 2008, and sealed to protect the plaintiff's identify.
Doctors conceded that the child was healthy and developing normally until her 18-month well-baby visit, when she received vaccinations against nine different diseases all at once (two contained thimerosal).
Days later, the girl began spiraling downward into a cascade of illnesses and setbacks that, within months, presented as symptoms of autism, including: No response to verbal direction; loss of language skills; no eye contact; loss of "relatedness;" insomnia; incessant screaming; arching; and "watching the florescent lights repeatedly during examination."
In its written concession, the government said the child had a pre-existing mitochondrial disorder that was "aggravated" by her shots, and which ultimately resulted in an ASD diagnosis. The girl and her family will now be compensated for the lifetime of care she will require. But its implications for the larger vaccine-autism debate, and for public health policy in general, are not as certain.
The claim is one of 4,900 autism cases currently pending in Federal "Vaccine Court."
Dr. Grout's Comment:
This news has been so quiet that almost the only person reporting it to date is David Kirby, author of the book, Evidence of Harm, which speaks to thimerosal (mercury) in vaccines. Kirby's full report can be read at http://www.huffingtonpost.com/david-kirby/government-concedes-vacci_b_88323.html
Saturday Night Live Spoofs Drug Ads Seasonale
February 2008
At a time when the drug industry is facing increasing criticism, the cast of "Saturday Night Live" has weighed in with a hilarious spoof of television drug ads.
The "commercial," modeled after the real advertising campaign for the birth control pill Seasonale, touts a fake pill, Annuale. The spoof uses similar pill packaging, actors and even the same pink chairs, sneakers and yoga mats depicted in the real ad.
Dr. Grout's Comment:
Here's the video:
http://well.blogs.nytimes.com/2008/02/25/saturday-night-live-takes-on-drug-ads/
Vaccine Companies Investigated for Manslaughter - Hep B vaccine
February 2008
According to Reuters, a formal investigation has been launched by French authorities against two managers from drug companies GlaxoSmithKline and Sanofi Pasteur. A second investigation for manslaughter has also been opened against Sanofi Pasteur MSD.
The investigations are in response to allegations that the companies failed to fully disclose side effects from an anti-hepatitis B drug used between 1994 and 1998.
During this time, close to two-thirds of the French population, and almost all newborn babies, received a hepatitis B vaccine. The vaccination campaign was halted after concerns rose over the shot's side effects.
Thirty plaintiffs, including the families of five people who died after the vaccination, have launched a civil action in the case against the drug companies.
Dr. Grout's Comment:
The main risk factors for hep B are IV drug abusers and those who engage in sex with multiple partners. So unless that describes the mother, why on earth would the baby need a hep B vaccine? Yet the shot is recommended for every baby born in a US hospital; parents need to know enough to refuse.
The immune and central nervous systems of a newborn infant simply are not ready to handle something as challenging as a vaccine. In most other countries, the hep B vaccine is given later in life. Even then, this vaccine is associated with numerous side effects including increased risk of multiple sclerosis and rheumatoid disease autoimmune diseases.
Diabetes study suddenly halted deaths from low blood sugar
February 2008
For decades, researchers believed that if people with diabetes lowered their blood sugar to normal levels, they would no longer be at high risk of dying from heart disease. But the New York Times reports a major federal study of more than 10,000 middle-aged and older people with type 2 diabetes has found that lowering blood sugar actually increased their risk of death, researchers reported Wednesday.
The researchers announced that they were abruptly halting that part of the study, whose surprising results call into question how the disease, which affects 21 million Americans, should be managed.
Among the study participants who were randomly assigned to get their blood sugar levels to nearly normal, there were 54 more deaths than in the group whose levels were less rigidly controlled. The patients were in the study for an average of four years when investigators called a halt to the intensive blood sugar lowering and put all of them on the less intense regimen.
Even though most people assumed that lower blood sugar was better, no one had rigorously tested the idea.
And there are troubling questions about what the study means for people who are younger and who do not have cardiovascular disease. Should they forgo the low blood sugar targets?
No one knows.
Dr. Grout's Comment:
Maybe you shouldn't fool with Mother Nature by using drugs etc to lower blood sugar. Maybe we should look at the diet, which has been proven to lower blood sugar and restore normal response of muscles to insulin.
Humira for juvenile rheumatoid arthritis - FDA gives approval
February 2008
Abbott Laboratories announced that its top-selling drug, Humira (adalimumab), has won approval from federal regulators to treat juvenile rheumatoid arthritis (RA). According to Abbott, "This is the sixth use for Humira approved by the Food and Drug Administration (FDA), and the second this year."
Humira "is approved in the U.S. to treat rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis, a spinal disorder; psoriasis; and Crohn's disease, a bowel disorder."
The FDA's approval was based on a study that found children with the disease were twice as likely to achieve 70 percent improvement of their symptoms as patients receiving a placebo, and were about a third less likely to experience a flare-up of the disease.
RA "is a condition in which inflammation causes joints -- usually including the hands and feet -- to become inflamed." Furthermore, the "painful swelling often leads to destruction of joints."
Dr. Grout’s comment:
Humira is a Tumor Necrosis Factor (TNF) blocker. Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis. In order to block the inflammatory response, are you willing to subject your child to side affects which include tuberculosis, invasive fungal infections, certain types of cancer (especially lymphoma), and autoimmune disorders (such as a lupus-like syndrome)? Humira is in the class of immunosupressants. Doesn't it make more sense to discover the sources of inflammation, and eliminate those? It would be less expensive for the families, and would promote a lifetime of heath, instead of a lifetime of disease management.
Leaky Gut Syndrome can definitely be a cause of Juvenile Rhuematoid Arthritis. With leaky gut, the common diet of processed food, antibiotics, and stress can set off a cascade of problems in the gut with inflammation of the gut lining causing swelling and separation of cells, allowing large molecules to leak into the blood stream. Some of these molecules look like our own proteins, and this can result in inflammation of the joints. Leaky gut must be addressed with diet or other problems will follow. Adults can experience the same phenomenon. It may also be called rheumatoid arthritis in adults. Seldom is the connection made between the gut and the joints, since these body systems are treated by different practitioners, in the conventional medical practice.
Largest beef recall in US history triggered by secret video
February 2008
The USDA announced recall of 143 million pounds of beef, the nation's largest recall to date.
The recall will affect beef products dating to February 1, 2006, that came from Chino, California's Westland/Hallmark Meat Co.
Most of the recalled beef has already been consumed. Of the 143 million pounds that were recalled, 37 million went to make hamburgers, chili, and tacos for school lunches and other federal nutrition programs, officials said.
Federal officials suspended operations at Westland/Hallmark after an undercover Humane Society of the United States video surfaced showing crippled and sick animals being shoved with forklifts and workers kicking, shocking and otherwise abusing animals that were apparently too sick or injured to walk to slaughter.
Secretary of Agriculture Ed Schafer said his department has evidence that Westland did not routinely contact its veterinarian when cattle became non-ambulatory after passing inspection, violating health regulations. "Because the cattle did not receive complete and proper inspection," he said, the government "has determined them to be unfit for human food."
Cows that cannot walk are banned for use in the food supply because they pose an added risk of mad cow disease, or bovine spongiform encephalopathy, a fatal disease that eats away at the brain.
"The longer-term problem is the inadequacies of the inspection system. How can so many downers have been mistreated day after day within a U.S.D.A. oversight system that was present at the plant?" asked Wayne Pacelle, president and chief executive of the Humane Society. "We need more boots on the ground at the plants."
Dr. Grout's Comment:
The Humane Society is to be applauded for bringing these conditions to light. If you have the stomach for it, you can watch their video at http://www.hsus.org/ This also is an argument for choosing organic beef because the animals are better treated. Organic ground beef also comes without hormones, steroids, and antibiotics.
Americans spend more to treat back pain it isn't working
February 2008
According to new research published in the Journal of the American Medical Association, "Americans are spending more money than ever to treat spine problems, but their backs are not getting any better."
University of Washington researchers examined annual household survey data from the Agency for Healthcare Research and Quality, which was collected from about 23,000 people a year from 1997 to 2005. They also used data from related surveys of doctors and pharmacists to estimate how much money was spent on various health conditions.
Researchers found that "the average medical expenditure for respondents who said they had spine problems was 73 percent greater than that of those who didn't." After they adjusted for inflation, researchers found that "medical expenditures by Americans with back or neck problems rose an estimated 65 percent from 1997 through 2005, more rapidly than health expenditures by Americans overall." Paradoxically, however, "the estimated proportion of people with spine problems who reported having physical function limitations rose from 20.7 percent to 24.7 percent during that same period."
In terms of actual expenditures, the research team estimates that "treating spine problems in the United States costs $85.9 billion a year, rivaling the economic burden of treating cancer, which costs $89 billion."
Study co-author Richard A. Deyo, M.D., M.P.H., said patients with pain have "reported more work limitations and poorer functioning in 2005 than in 1997," which indicates that "we're overtreating a lot of people, and we're providing a lot of services that may not be very beneficial." Dr. Deyo further notes that "the evidence [for surgery] is at best murky and confusing." In addition, Dr. Deyo stated, "patients need to recognize that" drugs such as Vicodin (hydrocodone bitartrate and acetaminophen) and OxyContin (oxycodone HCl) "have many potential side effects, including drowsiness, persistent constipation, and sexual dysfunction." And, he said, "We still don't know much about their long-term efficacy and safety for chronic back pain."
Dr. Grout's comment:
How sad, that we spend all this money on drugs, when acupuncture is proven to be so effective at treating back pain (and other pains as well). Acupuncture is inexpensive and effective why look any further, if you don't have to? It should definitely be a first choice, not a last resort.
FDA issues Botox & Chantix warnings aggressive behavior and deaths reported
February 2008
The FDA today notified the public that Botox and Botox Cosmetic (Botulinum toxin Type A) and Myobloc (Botulinum toxin Type B) have been linked in some cases to adverse reactions, including respiratory failure and death, following treatment of a variety of conditions using a wide range of doses.
In an early communication based on the FDA's ongoing safety review, the agency said the reactions may be related to overdosing. There is no evidence that these reactions are related to any defect in the products.
The adverse effects were found in FDA-approved and nonapproved usages. The most severe adverse effects were found in children treated for spasticity in their limbs associated with cerebral palsy. Treatment of spasticity is not an FDA-approved use of botulism toxins in children or adults.
The adverse reactions appear to be related to the spread of the toxin to areas distant from the site of injection, and mimic symptoms of botulism, which may include difficulty swallowing, weakness and breathing problems.
On February 1st, the FDA asked Pfizer, the manufacturer of Chantix, to update the Chantix prescribing information to include warnings about the possibility of severe changes in mood and behavior. Chantix is used to help patients stop smoking.
Chantix may cause worsening of a current psychiatric illness even if it is currently under control and may cause an old psychiatric illness to reoccur. Symptoms may include anxiety, nervousness, tension, depressed mood, unusual behaviors and thinking about or attempting suicide.
Dr. Grout's Comment:
The FDA is not advising health care professionals to discontinue prescribing these products. This kind of reaction from a government over-sight agency fuels the debate whether industry has too much influence upon the regulatory process at the FDA. At the very least, these are two more events in an on-going tide of bad news about adverse drug reactions. And these drugs are optional, so why take the risk?
Stunning reversal on food additives AAP says hyperactivity is real
February 2008
The American Academy of Pediatrics (AAP) has made a stunning reversal of its long standing position that dietary treatment is of no use in AD/HD. The AAP acknowledged findings of last September's Southampton/McCann study which demonstrated that common food colorings, derived from petroleum, and common preservatives cause hyperactivity in children.
In AAP's February 2008 issue of Grand Rounds, editors said:
"
this was a carefully conducted study in which the investigators went to great lengths to eliminate bias and to rigorously measure outcomes
the overall findings of the study are clear and require that even we skeptics, who have long doubted parental claims of the effects of various foods on the behavior of their children, admit we might have been wrong."
This opens the door to new AAP guidelines:
"Despite increasing data supporting the efficacy of stimulants in preschoolers with attention deficit hyperactivity disorder (AD/HD) parents and providers understandably seek safe and effective interventions that require no prescription
practitioners faced with hyperactive preschoolers have a reasonable option to offer parents. For the child without a medical, emotional, or environmental etiology of AD/HD behaviors, a trial of a preservative-free, food coloringfree diet is a reasonable intervention."
Dr. Grout's Comment:
AAP is the organization whose responsibility includes writing practice parameters which are guidelines for pediatricians to use in treating children. For most of the past 30 years, the AAP has maintained that dietary treatment is of no use in AD/HD.
This is a long-overdue, but extremely welcome reversal of position. Of course food matters! Children also consume food dye in their toothpaste, their shampoo (through the scalp), their hand lotion (through their skin), their cereal, their juice drinks, their mac 'n cheese, etc. In 1977 study, the National Academy of Sciences determined that most people in the United States eat up to an average of 317 mg of food dyes per day. You can read more at Kid Food - What is It? and Soda Pop-Obesity and Hyperactivity in a Can.
Vinyl toys unpopular retailers respond to safety concerns
February 2008
After recalling millions of toys to protect consumers from lead paint, toy makers face growing pressure over the plastic PVC - commonly known as vinyl - found in a myriad of playthings.
The Wall Street Journal reports some of the first plastic toys made without PVC will be shown at the world's largest toy trade show, the American International Toy Fair, which opens Sunday in New York.
Depending upon how it is made, PVC frequently contains lead or other toxic materials. Vinyl chloride, used to make PVC, has been identified as a carcinogen. Phthalates are often used to soften PVC-made toys and it has been linked to developmental and hormonal disruptions in children.
In 2003, The Consumer Product Safety Commission denied a petition from environmental groups to ban PVC in toys saying it didn't believe children chew on PVC toys long enough to cause harm. The Toy Industry Association says PVC in toys poses no safety risks.
Dr. Grout's Comment:
Here we see yet another case where concerned parents and environmental groups are taking the lead, putting pressure on toy manufacturers to lessen the body burden of chemicals. And the marketplace is responding. Phasing out PVCs is do-able. Because of proprietary concerns, we are not hearing yet much about the safety of what will be used instead. But one thing is clear: Where our children are concerned, safety should be everyone's first priority.
Fluorescent lights release toxic mercury campaign to switch has problems
February 2007
There is an international campaign to ban the incandescent bulb in favor of alternative sources of lighting, most notably fluorescents. Unfortunately, fluorescents contain noxious chemicals including argon and mercury that are contaminating the environment.
As Mike Adams of naturalnews.com reports, 800 million lamps produce enough mercury to contaminate about 20 million acres of water.
When the bulbs break, mercury can contaminate the environment, including soils, people and animals in the surrounding the area. Mercury is a potent neurotoxin that can severely harm the human nervous system through either ingestion, inhalation or skin absorption. It is a highly toxic heavy metal that acts as a cumulative poison similar to lead or DDT.
When the bulbs are recycled, a special hazardous waste company generally carries out the process of collecting the unbroken bulbs, crushing them and capturing both the remaining mercury gas and the spent mercury solids. These companies then ship the mercury-bearing waste, using an EPA-permitted hazardous waste transporter, to an EPA-approved hazardous waste treatment, storage and disposal facility.
Most compact fluorescent lights simply end up in landfill and are not recycled at all. Consumers simply throw them in the trash.
Dr. Grout's Comment:
Here is a case of the road to good intentions being paved with 3rd-rate planning. The EPA launched a campaign to get us to switch to fluorescent light bulbs in the name of energy savings. But they did not launch a safety education campaign at the same time. And most of all, they ignored the inherent and significant risk mercury presents to human health.
Most consumers couldn't tell you they are supposed to dispose of the compact fluorescents through "hazardous waste collection days" or certified waste recycling centers. And odds are, the bulbs will break before you get them there light bulbs are fragile!
Meanwhile - Norway, Sweden, Finland and Denmark have stated they intend to eventually eliminate mercury use completely, and plan on researching alternatives to fluorescent lighting such as LED technology.
Infertility helped with acupuncture successful and inexpensive
February 2008
According to findings published in today's issue of the British Medical Journal, "acupuncture might improve the odds of conceiving if done right before or after embryos are placed in the womb." Lead author Eric Manheimer, M.S., a researcher at the University of Maryland School of Medicine, and colleagues, conducted a meta-analysis of results from seven studies on 1,366 women in the United States, Germany, Australia, and Denmark who are having in vitro fertilization (IVF). Participants "were randomly assigned to receive IVF alone, IVF with acupuncture within a day of embryo transfer, or IVF plus sham acupuncture, in which needles were placed too shallowly, or in spots not thought to matter
three of the studies [considered] acupuncture beneficial," another "three found a trend toward benefit, and one found no benefit."
By combining study results, the researchers discovered a 65 percent increase in pregnancy, and an 87 percent increase in the continuity of the pregnancy. The results also showed a 91 percent increase in live births.
The analysis indicated that in studies where pregnancy rates were high, the benefit of acupuncture was small and non-significant. Manheimer noted that while "[a]cupuncture may be useful adjuvant treatment in the IVF process," he believes "there needs to be more studies to confirm these findings, because they are still preliminary."
Nevertheless, authors concluded that even if the likelihood of success with acupuncture were small, an acupuncture cointervention may still be cost effective, considering the negligible costs of two to four sessions of acupuncture, relative to the high costs of in vitro fertilization.
Dr. Grout's comment:
There are at least two acupuncturists in the Phoenix area who do acupuncture for fertility, both with great success. One is Pamela J. Wallach, LAc who practices out of our office. The other is Rebecca Wilks, MD, MD(H) whose office is in Glendale. Both report markedly increased rates of pregnancy after in-vitro fertilization, and excellent results even with patients who do not have IVF, but whom acupuncture helps conceive naturally. Acupuncture is certainly both less expensive and less dangerous than IVF. And when combined with excellent nutritional advice and appropriate vitamin and nutrient supplementation, what better start could a baby have?
Environmental chemicals bad for sex life Damage is passed through generations
February 2008
Common household chemicals and widespread pollutants are changing male reproductive health and impacting sexual function, development and cancer rates of today's generations and possibly their offspring, according to more than 15 years of research by a Colorado State University expert. For example, one study looking at sperm counts globally from 1940 - when chemicals first began to be widely produced - to the 1990s, indicates a 1.15 percent per year decline in sperm counts. These declines may be linked to chemical exposure.
Chemicals including insecticides, pesticides, common pollutants in ground water, and chemicals in plastics, make-up and nail polish are on a growing list of culprits causing developmental abnormalities such as hypospadias and cryptorchidism, impaired sperm quality and impotence. Reproductive health can be compromised if males are exposed at various times in life spanning from in utero up to adulthood.
Some of these chemicals can survive in the environment for 30 to 40 years, and the chances for exposure are high because the chemicals have permeated our world. The incidence of testicular cancer in young men 15 to 35 years old has increased three to four fold over the past 50 years, particularly in the Western world. Erectile dysfunction is reported in one-third of the U.S. male population.
Dr. Grout's Comment:
These chemicals affect the body through several channels. They attach to receptors in the body that help hormones carry out their functions and either block actual hormones from attaching or mimic the expression of the real hormones, causing confusion in the male body. In addition, some interfere with the body's natural production of hormones.
There is also evidence that exposure today to some of these chemicals can affect the reproductive health of this generation as well as the future health of offspring of those exposed. Watch a fascinating BBC program, called The Ghost in Your Genes.
Early puberty is earlier than ever is it normal?
January 2008
The first visible sign of puberty, breast budding, is arriving ever earlier in American girls as the Los Angeles Times reports.
Some parents and activists suspect environmental chemicals. Most pediatricians and endocrinologists say that, though they have suspicions about the environment, the only scientific evidence points to the obesity epidemic.
Earlier breast development is now so typical that the Lawson Wilkins Pediatric Endocrine Society urged changing the definition of "normal" development. Until 10 years ago, breast development at age 8 was considered an abnormal event that should be investigated by an endocrinologist. Then a landmark study in the April 1997 journal Pediatrics written by Marcia Herman-Giddens, adjunct professor at the School of Public Health at the University of North Carolina, Chapel Hill, found that among 17,000 girls in North Carolina, almost half of African Americans and 15% of whites had begun breast development by age 8. Two years later, the society suggested changing what it considered medically normal.
Dr. Grout's comment:
Experts like Theo Colborn, author of Our Stolen Future, and Dr. Doris Rapp, author of Our Toxic World, have shown how environmental chemicals are altering the reproductive nature of many species, including humans. (See news brief of 2-5-08.) The medical community only wants to acknowledge that obesity is part of the cause - fatty tissue is a source of estrogen, so chubbier girls are exposed to more estrogen. But fatty tissue also holds toxic chemicals, what is called the Body Burden. The medical community may decide to declare precocious puberty "normal," but explain that to the mother whose 8-year old girl is still playing with dolls and now needs to be told the fundamentals of sex.
Majority do not benefit from statins high cholesterol problem overstated
January 2008
James M. Wright, professor at the University of British Columbia and director of the government-funded Therapeutics Initiative, analyzed evidence from years of trials with statins.
According to Business Week magazine, Wright found no benefit in people over the age of 65, no matter how much their cholesterol declines, and no benefit in women of any age. He did see a small reduction in the number of heart attacks for middle-aged men taking statins in clinical trials. But even for these men, there was no overall reduction in total deaths or illnesses requiring hospitalizationdespite big reductions in "bad" cholesterol. "Most people are taking something with no chance of benefit and a risk of harm," says Wright.
To statin critics, Americans have come to rely too much on easy-to-grasp health markers. People like to have a metric, such as cholesterol levels, that can be monitored and altered. "Once you tell people a number, they will be fixated on the number and try to get it better," says Dr. Howard Brody, professor of family medicine at the University of Texas Medical Branch at Galveston. "The American cultural norm is that doing something makes us feel better than just watching and waiting," says Barry. That applies to doctors as well. They are being pushed by the national guidelines, by patients' own requests, and by pay-for- performance rules that reward physicians for checking and reducing cholesterol. "I bought into it," Brody says. Not to do so is almost impossible, he adds. "If a physician suggested not checking a cholesterol level, many patients would stomp out of the office claiming the guy was a quack."
Yet Brody changed his mind. "I now see it as myth that everyone should have their cholesterol checked," he says. "In hindsight it was obvious. Duh! Why didn't I see it before?"
Dr. Grout's comment:
It is the purpose of the Theraputic Initiative to pore over the data on particular drugs and figure out how well they work. It is extremely heartening to see that finally the word is getting out in the media that high cholesterol does not usually need to be treated with drugs of very questionable value. Meanwhile, many people have reported debilitating problems with statins, including muscle weakness, fatigue, dizziness, and lessened cognitive function. When high cholesterol is a sign of inflammation in the arteries, better to reduce the trans fats, sugars, and environmental toxins that feed the inflammation.
Worrisome phthalate levels in infant urine Babies are contaminated
February 2008
A study publi |